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Poultry Diagnostic and Research Center





Regents' Professor Emeritus

Poultry Diagnostic Research Center
953 College Station Road
Athens, Georgia 30602-4875
706.542.5644
e-mail: Skleven@uga.edu




Professional Experience:
Veterinary Practitioner, large animal practice, Hettinger, North Dakota, 1965-1966.
University of Minnesota, Department of Veterinary Microbiology and Public Health, Instructor, 1966-1967, Non-Service Fellow, 1967-1970.
University of Georgia, Department of Avian Medicine, Athens, Georgia, Assistant Professor, 1970-1973, Associate Professor, 1973-1978, Professor, 1978 to present,
Research Professor, 1990-2000; Distinghished Research Professor, 2000-2002;
Regents’ Professor, 2002-present; Actinq Head, December, 1971 to May 1972, and July, 1989 to February, 1990, Head, May 1972 to September, 1982, and February, 1990 to 1 September, 2003. Member of Graduate Faculty, 1971 to present.
Department of Paraclinical Sciences, School of Veterinary Science, University of Melbourne. Visiting Professor, January-July, 1987.

 

Education:
1958 - 1960 St. Olaf College, Northfield, Minnesota
1960 - 1965 University of Minnesota, St. Paul, Minnesota, B.S., 1965
D.V.M. With Highest Honors, 1970
1966 - 1970 University of Minnesota, St. Paul, Minnesota, Ph.D., 1970
Major: Veterinary Microbiology
Minor: Biochemistry

 

Specialty Boards:
Diplomate, American College of Veterinary Microbiologists
Charter Diplomate, American College of Poultry Veterinarians

 

Research Interests:
Infectious diseases of poultry, specifically avian mycoplasmosis

 

Recent Publications:
Bradbury, J. M., and S. H. Kleven Mycoplasma iowae infection. In: Diseases of Poultry, 12 ed. Y. M. Saif, A. M. Fadly, J. R. Glisson, L. R. McDougald, N. K. Nolan and D. E. Swayne, eds. Blackwell Publishing, Ames, Iowa. pp 856-862. 2008.

Kleven, S. H. Mycoplasmosis. In: A Laboratory Manual for the Isolation, Identification, and Characterization of Avian Pathogens. L. Dufour-Zavala, D. E. Swayne, J. R. Glisson, J. E. Pearson, W. M. Reed, M. W. Jackwood and P. R. Woolcock, eds. American Association of Avian Pathologists, Athens, GA. pp 59-64. 2008.

Kleven, S. H. Mycoplasmosis. Introduction. In: Diseases of Poultry, 12 ed. Y. M. Saif, A. M. Fadly, J. R. Glisson, L. R. McDougald, N. K. Nolan and D. E. Swayne, eds. Blackwell Publishing, Ames, Iowa. pp 805-807. 2008.

Kleven, S. H. Multicausal Respiratory Disease. In: Diseases of Poultry, 12 ed. Y. M. Saif, A. M. Fadly, J. R. Glisson, L. R. McDougald, N. K. Nolan and D. E. Swayne, eds. Blackwell Publishing, Ames, Iowa. pp 1262-1266. 2008.

Kleven, S. H. Other Mycoplasmal infections. In: Diseases of Poultry, 12 ed. Y. M. Saif, A. M. Fadly, J. R. Glisson, L. R. McDougald, N. K. Nolan and D. E. Swayne, eds. Blackwell Publishing, Ames, Iowa. pp 862-864. 2008.

Kleven, S. H., and J. M. Bradbury Avian Mycoplasmosis (Mycoplasma gallisepticum, M. synoviae). In: Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, Sixth ed. World Organization for Animal Health, Paris. pp 482-496. 2008.

Kleven, S. H., and N. Ferguson-Noel Mycoplasma synoviae infection. In: Diseases of Poultry, 12 ed. Y. M. Saif, A. M. Fadly, J. R. Glisson, L. R. McDougald, N. K. Nolan and D. E. Swayne, eds. Iowa State University Press, Ames, Iowa. pp 845-856. 2008.

Raviv, Z., S. A. Callison, N. Ferguson-Noel, and S. H. Kleven. Strain differentiating real-time PCR for Mycoplasma gallisepticum live vaccine evaluation studies. Vet. Microbiol. 129:179-187. 2008.

Callison, S. A., S. M. Riblet, S. Sun, N. Ikuta, D. Hilt, V. Leiting, S. H. Kleven, D. Suarez, M. Garcia. Development and validation of a Real-Time Taqman PCR assay for the detection of Mycoplasma gallisepticum in naturally infected birds. Avian Dis. Avian Dis. 50:537-544. 2007.

Raviv, Z., S. A. Callison, N. Ferguson-Noel, V. Laibinis, R. Wooten, and S. H. Kleven. The Mycoplasma gallisepticum 16S-23S rRNA Intergenic Spacer Region Sequence, as a Novel Tool for Epizootiological Studies Avian Dis. 51:555-560. 2007.

Raviv, Z., N. Ferguson-Noel, V. Laibinis, R. Wooten, and S. H. Kleven. Role of Mycoplasma synoviae in Commercial Layer E. coli Peritonitis Syndrome Avian Dis. 51:685-690. 2007.

Kleven, S. H., N. Ferguson-Noel, Z. Raviv, R. Wooten, and V. Laibinis. Serological Responses of Chickens to Low Challenge Doses of Mycoplasma synoviae. Avian Dis. 51:738-743. 2007.

May, M., S. H. Kleven, and D. R. Brown. Sialidase activity in Mycoplasma synoviae. Avian Dis. 51:829-833. 2007.

Mettifogo, E., M. Buzinhani, M. R. Buim, A. J. Piantino Ferreira, S. H. Kleven, and J. Timenetsky. Molecular Characterization of MG Isolates Using RAPD and PFGE Isolated from Chickens in Brazil. J. Vet. Med. B 53:445-450. 2006.

Callison, S. A., S. M. Riblet, S. Sun, N. Ikuta, D. Hilt, V. Leiting, S. H. Kleven, D. L. Suarez, and M. Garcia. Development and validation of a Real-Time Taqman® polymerase chain reaction assay for the detection of Mycoplasma gallisepticum in naturally infected birds. Avian Dis. 50:537-544. 2006.

Ferguson, N.M., D. Hepp, S. Sun, N. Ikuta, S. Levisohn, S.H. Kleven, and M. García. Use of molecular diversity of Mycoplasma gallisepticum by gene-targeted sequencing (GTS) and random amplified polymorphic DNA (RAPD) analysis for epidemiological studies. Microbiol. In Press. 2005.

García, M., N. Ikuta, S. Levisohn, and S.H. Kleven. Evaluation and Comparison of Various PCR Methods for Detection of Mycoplasma gallisepticum Infection in Chickens. Avian Dis. 48:125-132. 2005.

Hong, Y., M. Garcia, S. Levisohn, P. Savelkoul, V. Leiting, I. Lysnyansky, D.H. Ley, and S.H. Kleven. Differentiation of Mycoplasma gallisepticum strains using amplified fragment length polymorphism and other DNA-Based Typing Methods. Avian Dis. 49:43-49. 2005.


Hong, Y., M. García, S. Levisohn, I. Lysnyansky, V. Leiting, P.H.M. Savelkoul, and S.H. Kleven. Evaluation of Amplified Fragment Length Polymorphism for Differentiation of Avian Mycoplasma Species. J. Clin. Microbiol. 43:909-912. 2005.

Zaki, M., N. Ferguson, V. Leiting, and S.H. Kleven. Safety of Mycoplasma gallisepticum vaccine strain 6/85 after backpassage in turkeys. Avian Dis. 48:642-646. 2004.

Moscoso, H., S.G. Thayer, C.L. Hofacre, and S.H. Kleven. Inactivation, Storage, and PCR Detection of Mycoplasma on FTA® Filter Paper. Avian Dis. 48:841-850. 2004.

Kleven, S.H., F.T.W. Jordan, and J.M. Bradbury, Avian Mycoplasmosis (Mycoplasma gallisepticum), in Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, Five th.Office International des Epizooties: Paris. p. 842-855. 2004.

Kleven, S.H., R.M. Fulton, M. Garcia, V.N. Ikuta, V.A. Leiting, T. Liu, D.H. Ley, K.N. Opengart, G.N. Rowland, and E. Wallner-Pendleton. Molecular characterization of Mycoplasma gallisepticum isolates from turkeys. Avian Dis. 48:562-569. 2004.

Lobo, E., M.C. Garcia, H. Moscoso, S. Martinez, and S.H. Kleven. Strain heterogeneity in Mycoplasma pullorum isolates identified by random amplified polymorphic DNA techniques. Sp. J. Ag. Res. 2:500-503. 2004.

Ferguson, N.M., V.A. Leiting, and S.H. Kleven. Safety and efficacy of an avirulent Mycoplasma gallisepticum strain as a live vaccine in poultry. Avian Dis. 48:91-99. 2004.

Hong, Y., M. García, L. Leiting, D. Bencina, L. Dufour-Zavala, G. Zavala, and S.H. Kleven. Specific Detection and Typing of Mycoplasma synoviae Strains in Poultry with PCR and DNA Sequence Analysis Targeting the Hemagglutinin Encoding Gene vlhA. Avian Dis. 48:606-616. 2004.

Throne Steinlage, S.J., N. Ferguson, J.E. Sander, M. García, S. Subramanian, V.A. Leiting, and S.H. Kleven. Isolation and characterization of a 6/85-like Mycoplasma gallisepticum from commercial laying hens. Avian Dis. 47:499-505. 2003.

Luttrell, M.P., J.R. Fischer, and S.H. Kleven. Susceptibility of House Finches (Carpodacus mexicanus) to Poultry Strains of Mycoplasma gallisepticum. Avian Dis. In preparation: 2003.

Kleven, S.H., Multicausal Respiratory Disease, in Diseases of Poultry, 11 th. ed. B.W. Calnek, et al., Editors.Iowa State University Press: Ames, Iowa. p. 1164-1168. 2003.

Kleven, S.H., Multifactorial respiratory disease and Mycoplasmas, in World Poultry. 2003. p. 2-3.

Kleven, S.H., Mycoplasma synoviae infection, in Diseases of Poultry, 11 th. ed. Y.M. Saif, et al., Editors.Iowa State University Press: Ames, Iowa. p. 756-766. 2003.

Kleven, S.H., Mycoplasmas and multifactorial respiratory disease, in World Poultry. 2003. p. 6-7.

Kleven, S.H., Mycoplasmosis. Introduction, in Diseases of Poultry, 11 th. ed. Y.M. Saif, et al., Editors.Iowa State University Press: Ames, Iowa. p. 719-721. 2003.

Kleven, S.H., Other Mycoplasmal infections, in Diseases of Poultry, 11 th. ed. Y.M. Saif, et al., Editors.Iowa State University Press: Ames, Iowa. p. 772-774. 2003.

Kleven, S.H. and M. García. Epidemiology of Mycoplasmal infections based on analyses of gene polymorphisms. FEMS Microbiol. Lett. 222 S1:101. 2003.

Ferguson, N.M., D. Hermes, V.A. Leiting, and S.H. Kleven. Characterization of a naturally occurring Infection of a Mycoplasma gallisepticum house finch-like strain in turkey breeders. Avian Dis. 47:523-530. 2003.

Bradbury, J.M. and S.H. Kleven, Mycoplasma iowae infection, in Diseases of Poultry, 11 th. ed. Y.M. Saif, et al., Editors.Iowa State University Press: Ames, Iowa. p. 766-771. 2003.

Kang, M.S., P. Gazdzinski, and S.H. Kleven. Virulence of recent isolates of mycoplasma synoviae in turkeys. Avian Dis. 46:102-10. 2002.

Kleven, S.H. Recent developments in Mycoplasma diagnosis and control. Proc. Western Poult. Dis. Conf. 51:109-113. 2002.

Liu, T., M. Garcia, S. Levisohn, D. Yogev, and S.H. Kleven. Molecular Variability of the Adhesin-Encoding Gene pvpA among Mycoplasma gallisepticum Strains and Its Application in Diagnosis. J. Clin. Microbiol. 39:1882-1888. 2001.

Luttrell, M.P., D.E. Stallknecht, S.H. Kleven, D.M. Kavanaugh, J.L. Corn, and J.R. Fischer. Mycoplasma gallisepticum in house finches (Carpodacus mexicanus) and other wild birds associated with poultry production facilities. Avian Dis. 45:321-329. 2001.

Stanley, W.A., C.L. Hofacre, G. Speksnijder, S.H. Kleven, and S.E. Aggrey. Monitoring Mycoplasma gallisepticum and Mycoplasma synoviae infection in breeder chickens after treatment with enrofloxacin. Avian Dis. 45:534-539. 2001.

Bencina, D., M. Drobnic-Valic, S. Horvat, M. Narat, S.H. Kleven, and P. Dovc. Molecular basis of the length variation in the N-terminal part of Mycoplasma synoviae hemagglutinin. FEMS Microbiol Lett. 203:115-23. 2001.

Elfaki, M.G., B. Abbas, O.M. Mahmoud, and S.H. Kleven. Isolation and characterization of Mycoplasma arginini from camels (Camelus dromedarius) with pneumonia. Comp Immunol Microbiol. Inf. Dis. 25:49-57. 2001.
Kleven, S.H., G.N. Rowland, and M.C. Kumar. Poor serological response to upper respiratory infection with Mycoplasma synoviae in turkeys. Avian Dis. 45:719-723. 2001.

Kleven, S.H., F.T.W. Jordan, and J.M. Bradbury, Avian Mycoplasmosis (Mycoplasma gallisepticum), in Manual of Standards for Diagnostic Tests and Vaccines, Four th.Office International des Epizooties: Paris. p. 666-678. 2000.

Leiting, V.A. and S.H. Kleven. Preparation of a heterogeneous conjugate to detect Mycoplasma iowae by immunofluorescence. Avian Dis. 44:697-700. 2000.

Levisohn, S. and S.H. Kleven. Avian mycoplasmosis (Mycoplasma gallisepticum). Rev. sci. tech. Off. int. Epiz. 19:425-442. 2000.

 

 

This page last updated September 2008