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Professor Poultry Diagnostic Research Center Web site: Coronavirus Research |
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Dr. Mark W. Jackwood is a Professor in the College of Veterinary Medicine, Department of Avian Medicine, at the Poultry Diagnostic and Research Center, University of Georgia, Athens GA. He earned his Ph.D. degree in the Department of Poultry Science at The Ohio State University. Dr. Jackwood is a Molecular Virologist and his primary area of research is the study of avian coronaviruses. Specifically he works with infectious bronchitis virus (IBV), a coronavirus that causes an upper-respiratory disease in chickens, and turkey coronavirus (TCoV) an enteric disease in turkeys, which is also associated with poult enteritis mortality syndrome (PEMS). Dr. Jackwood’s work involves the use of molecular techniques for the identification, characterization, and control of those viruses. |
Education:
Univ. Delaware Animal Science BS 1978
Univ. Delaware Virology MS 1982
The Ohio State Univ. Microbiology Ph.D. 1985
Recent publications:
Escorcia, M., Jackwood, M.W., Lucio, B., Petrone, V.M.,
López, C., Fehervari, T., and Tellez, G.
Characterization of Mexican strains of avian infectious bronchitis ioslated
during 1997.
Avian Dis., 44: 944-947. 2000.
Jones, C., Newby, T.J., Holt, T., Doster, A., Stone, M., Ciacci-Zanella, J., Webster, C.J., Jackwood, M.W. Analysis of latcency in cattle after inoculation with a temperature sensitive mutant of bovine herpevirus 1 (RLB106). Vaccine 18: 3185-3194. 2000.
Lee, C.W. and Jackwood, M.W. Evidence of genetic diversity generated by recombination among avian coronavirus IBV. Arch. of Virol. 145: 2135-2148. 2000.
Lee, C-W., Hilt, D.A., and Jackwood, M.W. Redesign of Primer and Application of the Reverse Transcriptase-Polymerase Chain Reaction and Restriction Fragment Length Polymorphism Test to the DE072 Strain of Infectious Bronchitis Virus. Avian Dis. 44:650-654. 2000.
Callison, S.A., Jackwood, M.W., and Hilt D.A. Research
Note - Molecular Characterization of
Infectious Bronchitis Virus Isolates Foreign to the United States and
Comparison with United States
Isolates. Avian Dis. 45:492-499. 2001.
Jackwood, M. W., Hilt, D.A., Callison, S.A., Lee, C-W,
Plaza, H., and Wade E.D. Spike Glycoprotein
Cleavage Recognition Site Analysis of Infectious Bronchitis Virus. Avian
Dis. 45:366-372. 2001.
Lee, C.W. and Jackwood, M.W. Spike Gene Analysis of
the DE072 Strain of Infectious Bronchitis
Virus: Origin and Evolution. Virus Genes 22:1, 85-91. 2001.
Lee, Chang-Won, and Jackwood, M.W.: Origin and Evolution
of Georgia 98 (GA98), a New
Serotype of Avian Infectious Bronchitis Virus. Virus Res. 80:33-39. 2001.
Lee, C-W., Hilt, D.A., and Jackwood, M.W. Identification
and Analysis of the Georgia 98
Serotype, a New Serotype of Infectious Bronchitis Virus. Avian Dis. 45:164-172.
2001.
Kapczynski, D.R., Sellers, H.S., Rowland, G.N., and Jackwood, M.W.: Detection of in ovo-inoculation infectious bronchitis virus by immunohistochemistry and in situ hybridization with a riboprobe in epithelial cells of the lung and cloacal bursa. Avian Dis. 46:679-685. 2002.
Lee, C-W., Brown, C.C., and Jackwood, M.W. Tissue distribution of avian infectious bronchitis virus following in ovo inoculation of chicken embryos examined by in situ hybridization with antisene digoxigenin-labeled universal riboprobe. J. Vet. Diagn. Invest. 14:377-381. 2002.
Newby, T.J., Carter, D.P., Yoon, K.-J., Jackwood, M.W., and Hawkins, P.A. Assessment of Replication and Virulence of Attenuated Pseudorabies Virus in Swine. J. Vet. Sci. 3:61-66. 2002.
Kapczynski, D.R., Sellers, H.S., Rowland, G.N., and Jackwood, M.W. Detection of in ovo inoculated infectious bronchitis virus and in situ hybridization with a riboprobe in epithelial cells of the lung and cloacal bursa. Avian Dis. 46:679-685. 2002
Zavala, G., Jackwood, M.W., and Hilt, D.A.: Polymerase
chain reaction for detection of avian
leukosis virus subgroup J in feather pulp. Avian Dis. 46:971-978. 2002.
Zavala, G., Dufour-Zavala, L., Villegas, P., El-Attrache, J., Jackwood,
M.W., and Hilt, D.A.:
Lack of interaction between avian leucosis virus subgroup J (ALV-J) and
fowl adenovirus (FAV)
in FAV-antibody-positive chickens. Avian Dis. 46:979-984. 2002.
Lee C-W., D. A. Hilt, M. W. Jackwood. Typing of field
isolates of infectious bronchitis virus based
on the sequence of the hypervariable region in the S1 gene. J. Vet. Diagn.
Invest. 15:344-348. 2003.
Jackwood, M.W., Hilt, D.A., and Brown, T.P. Attenuation,
Safety and Efficacy of the GA98 Serotype
of Infectious Bronchitis. Avian Dis. 47:122-127. 2003.
Jackwood, M.W., Hilt, D.A., and Callison, S.A. Detection of Infectious Bronchitis Virus by Real-Time Reverse Transcriptase-Polymerase Chain Reaction and Identification of a Quasispecies in the Beaudette Strain. Avian Dis. 47:128-134. 2003.
Kapczynski, D. R., D. A. Hilt, D. Shapiro, Seller, H.S., and M. W. Jackwood. Protection of chickens from infectious bronchitis by in ovo and intramuscular vaccination with a DNA vaccine expressing the S1 glycoprotein. Avian Dis. 47:272-285. 2003.
Lee, C-W, C. Brown, D. A. Hilt, and M. W. Jackwood. Nephropathogenesis of chickens experimentally infected with various strains of infectious bronchitis virus. J. Vet. Med. Sci. 66:835-840. 2004
Jackwood, M. W., Hilt, D., and Callison, S.: Turkey Coronavirus Spike Glycoprotein Gene Sequence and Evolutionary Relationships to Other Coronaviruses. 140th Annual Convention of the American Veterinary Medical Association. July 19-23, 2003.
Jackwood, M. W., D. A. Hilt, T. Boynton, and S. A. Callison. Molecular analysis of TCoV, SARS-CoV, and IBV: how are they related. p. 158-165, Proceedings of the 4th International Symposium on Avian Corona- and Pneumovirus Infections, Rauischholzhausen, Germany. June 20-23, 2004.
Callison, S. A., D. A. Hilt, and M. W. Jackwood. Rapid differentiation of avian infectious bronchitis virus isolates by sample to residual ration quantitation using real-time reverse transcriptase-polymerase chain reaction. J. Virol. Meth. 124:183-190. 2005.
Callison, S. A., D. A. Hilt, and M. W. Jackwood. Using DNA shuffling to create novel infectious bronchitis virus S1 genes: Implications for S1 gene recombination. Virus Genes. Accepted January 2005.
Callison, S. A., D. A. Hilt, and M. W. Jackwood. In vitro analysis of a hammerhead ribozyme targeted to infectious bronchitis virus nucleocapsid mRNA. Avian Dis. 49:103-107. 2005.
This page last updated June 27, 2008

