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 Associate Professor, Poultry Diagnostic Research Center |
 |
Position: Post doc position available for establishment of reverse genetics systems for avian paramyxovirus. Please contact: emundt@uga.edu
Education
1989 DVM at Humboldt-University in Berlin
1995 Graduation as ‘Dr. med. vet.’
at the University Giessen, (PhD)
2000 Veterinary Specialist for Virology
2002 Graduation (Habilitation) as Dr. rer. med.
habil. for Virology at the University of Greifswald
Professional Experience
1989 – 1991 Employed as scientist at the Friedrich-Loeffler-Institutes,
Insel Riems, Germany. Research on avian herpesvirus
1991 Research at Institute of Virology, Justus -Liebig-
University Giessen, Germany (Head Prof. Rott)
Aug – Nov. 1995 Visiting scientist at University
of Maryland, Virginia-Maryland Regional College of Veterinary Medicine,
USA
1992-2006 Employed as scientist and group leader at Federal
Research Institute for Animal Health, Insel Riems, Germany,
Research interests and duties: Research on IBDV, IPNV, Influenza virus,
Newcastle disease virus, fish rabhdoviruses, porcine circovirus I and
II, Trichinella spiralis
Since Aug 1st 2006 PDRC, University of Georgia
Membership in scientific boards
Since 1996 Member of the Birnaviridae study group for
international taxonomy of viruses (ICTV)
1998-2004 Member of the management committee of a COST
action of the European union (EU-COST 839 “Immunosuppressive viral
diseases in poultry”,
homepage: http://home.pages.at/cost839/)
1998-2001 Vice-coordinator of the work group „Vaccination“
of the COST action 839
2001-2004 Coordinator of the work group „Vaccination“
of the COST action 839
1999 External referee of the university grants committee
of the University of Hong Kong, China
2005 External referee for PhD thesis University of Faisalabad,
Pakistan
2006 External referee for the German Research Foundation
2006 External referee for U.S. Civilian Research &
Development Foundation (CRDF)
2008 External referee for USDA/FAS/OCBD
2009 External referee of the university grants committee
of the University of Hong Kong, China
2009 External referee for the Portuguese Foundation for
Science and Technology
Awards
1997 Karl-Fritzsche-Stiftungspreis (Award of
the Karl-Fritzsche-Foundation) awarded from the German Veterinary
Medical Society
2003 Förderpreis 2002 (Award of the German
Academy for Animal Health)
Membership in scientific organizations
German Veterinary Medical Society
American Society for Virology
German Society for Virology
American Association of Avian Pathologist
American Society for Microbiology
American Veterinary Medical Association
Publications
Mundt, E., Gay, L., Jones, L., Saavedra, G., Tompkins, S. M. and Tripp,
R. A. (2009). Replication and Pathogenesis Associated with H5N1, H5N2
and H5N3 Low Pathogenic Avian Influenza Virus Infection in Chickens and
Ducks. Arch. in Virol. 154:1241-1248.
Sellers, H., Linneman, E., Icard, A. H., and Mundt, E (2009). A purified
recombinant baculovirus expressed capsid protein of a new astrovirus provides
partial protection to runting-stunting syndrome in chickens. Vaccine.
2009 Nov 23. [Epub ahead of print]
Avellaneda, G., Mundt, E., Lee, C-W, and Suarez, D. L. (2009). Differentiation
of infected and vaccinated animals (DIVA) using the NS1 protein of avian
influenza virus. Avian Dis., in press
Dlugolenski, D. Hauck, R., Hogan, R. J., Michel, F., and Mundt, E. (2009).
Production of H5 specific monoclonal antibodies and the development of
a competitive ELISA for detection of H5 antibodies in multiple species.
Avian Dis., in press
Gay, Lauren, and Mundt E. (2009). Testing of a New Disinfectant Process
for Poultry Viruses. Avian Dis., in press
Liu, Y., Mundt E., Mundt A., Sylte M., Swayne D. and M. García
(2009). Development and evaluation of an avian influenza (AI) neuraminidase
subtype 1 (N1) based serological ELISA for poultry using the differentiation
of infected and vaccinated animals (DIVA) control strategy. Avian Dis.,
in press
Icard, A.H., Sellers, H.S and Mundt, E. (2008). Detection of Infectious
Bursal Disease Virus isolates with unknown antigenic properties by reverse
genetics. Avian Dis., 52: 590–598
Warke, A., and Mundt, E. (2008). Prevalence of Antibodies to different
Avian Paramyxoviruses in Commercial Poultry in the USA. Avian Dis. 52:694-697
Warke, A., Stallknecht, D., Williams, S.M., Pritchard, N., and Mundt, E. (2008). Comparative study on the pathogenicity and immunogenicity of wild bird isolates of avian paramyxovirus 2, 4, and 6 in chickens.Avian Pathol. 37:429-434.
Letzel, T., Coulibaly, F., Rey, F. A., Delmas, B., Jagt, E.,van Loon, A. A. M. W., and Mundt, E. (2007). Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus. Journal of Virology, 81:12827-12835.
Letzel, T. Mundt, E. , and Gorbalenya, A. E. (2007). Evidence for functional significance of the permuted C motif in Co2+-stimulated RNA-dependent RNA polymerase of infectious bursal disease virus, Journal of General Virology, 88: 2824-2833.
Jung, D., Teifke. J P., Karger, A., Michael, K. ,Venz, S.,Wittmann, W., Kindermann, K.,Nöckler, K., and Mundt, E. (2007). Evaluation of baculovirus-derived recombinant 53 kDa protein of Trichinella spiralis for detection of Trichinella-specific antibodies in domestic pigs by ELISA. Parasitology Research, 100:429-437.
Weber, S., Harder, T., Starick, E., Beer, M., Werner, O., Hoffmann, B., Mettenleiter, Th. C., and and Mundt, E. (2007). Molecular analysis of highly pathogenic avian influenza virus of subtype H5N1 isolated from wild birds and mammals in Northern Germany. Journal of General Virology 88: 554-558.
Mundt, E. (2007). Human MxA Protein Confers Resistance to double-stranded RNA viruses of two virus families. Journal of General Virology, 88:1319-1323.
Jung, D., Teifke. J P., Karger, A., Michael, K. ,Venz, S.,Wittmann, W., Kindermann, K.,Nöckler, K., and Mundt, E. (2007). Evaluation of baculovirus-derived recombinant 53 kDa protein of Trichinella spiralis for detection of Trichinella-specific antibodies in domestic pigs by ELISA. Parasitology Research., 100:429-437
Weber, S., Harder, T., Starick, E., Beer, M., Werner, O., Hoffmann, B., Mettenleiter, Th. C., and and Mundt, E. (2007). Molecular analysis of highly pathogenic avian influenza virus of subtype H5N1 isolated from wild birds and mammals in Northern Germany. Journal of General Virology, 88: 554-558
Wolf, P.U., Uhl, W.Gerst, S., Gerst, K., Klopries, M., Teifke, J. P., Klopffleisch, R., Harder, T., Werner, O., Hoffmann, B., Starick,.E., Mundt, E., Beer, M., Mettenleiter, Th. C. (2006). Letal verlaufende Influenza bei Hauskatzen nach natürlicher Infektion mit H5N1/Asia in Deutschland. Deutsches Tierärzteblatt 54, 426-431.
Klopfleisch, R., Werner, O., Mundt, E., Harder, T., and Teifke, J. P. (2006). Neurotropism of highly pathogenic avian influenza virus A/chicken/Indonesia/2003 (H5N1) in experimentally infected pigeons (Columbia livia f. domestica). Veterinary Pathology. 43, 463-470.
Veits, J., Wiesner, D., Fuchs, W., Hoffmann, B., Granzow, H., Starick, E., Mundt, E., Schirrmeier, H., Mebatsion, T., Mettenleiter T. C., and Romer-Oberdorfer A. (2006) Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza. Proc Natl Acad Sci U S A. 103, 8197-8202.
Starick, E., Werner, O., Schirrmeier, H., Köllner, B., Riebe, R. and Mundt, E. (2006). Establishment of a competitive ELISA (cELISA) system for the detection of influenza A virus nucleoprotein antibodies and its application to field sera from different species. Journal Veterinary Medicine B 53, 370-375
Klupp, B.G., Granzow, H., Fuchs, W., Mundt, E., and Mettenleiter, T. C. (2004). Pseudorabies Virus UL3 Gene Codes for a Nuclear Protein Which Is Dispensable for Viral Replication. Journal of Virology 78: 464-472.
von Einem, U. I., Gorbalenya, A. E., Schirrmeier, H., Behrens, S. E., Letzel, T. and Mundt, E.. (2004). VP1 of Infectious Bursal Disease Virus is a RNA-Dependent RNA Polymerase. Journal of General Virology, 85: 2221-2229.
Delmas, B., Kibenge, F.S.B., Leong, J.C., Mundt, E., Vakharia, V.N. and Wu, J.L. (2004). Birnaviridae. In: Virus Taxonomy, VIIIth Report of the ICTV (C.M. Fauquet, M.A. Mayo, J. Maniloff, U. Desselberger, and L.A. Ball, eds), 561-569. Elsevier/Academic Press, London.
Kopp, M., Granzow, H., Fuchs, W., Klupp, B. G., Mundt, E., Karger, A., and Mettenleiter, T. C. (2003). The pseudorabies virus UL11 protein is a virion component involved in secondary envelopment in the cytoplasm. Journal of Virology 77, 5339-5351.
Zorman-Rojs, O., Barlic-Maganja, D., Mitevski, D., Lubke, W., and Mundt, E. (2003). Very virulent infectious bursal disease virus in southeastern Europe. Avian Dis. 47: 186-192.
Mundt, E., de Haas, N, and van Loon, A. A. W. M. (2003). Development of a vaccine for immunization against classical as well as variant strains of infectious bursal disease virus using reverse genetics. Vaccine, in press
van Loon, A. A., de Haas, N. , Zeyda, I. , and Mundt, E. (2002). Alteration of amino acids in VP2 of very virulent infectious bursal disease virus results in tissue culture adaptation and attenuation in chickens. Journal of General Virology 83: 121-129.
Schröder, A., van Loon, A. A. W. M., Goovaerts, D., Teifke, J. P., and Mundt, E. (2001). VP5 and the N terminus of VP2 are not responsible for the different pathotype of serotype I and II infectious bursal disease virus. Journal of General Virology, 82: 159-169.
Weber, S., Fichtner, D., Mettenleiter, T.C., and Mundt, E. (2001). Expression of VP5 of infectious pancreatic necrosis virus strain VR299 is initiated at the second in frame startcodon. Journal of General Virology 82:805 – 812
Klupp, B. G., Granzow, H., Mundt, E., and Mettenleiter, T. C. (2001). Pseudorabies virus ul37 gene product is involved in secondary envelopment. Journal of Virology 75:8927-8936
Granzow, H., Weiland, F., Fichtner, D., Schütze, H., Karger, A., Mundt, E., Dresenkamp, B., Martin, P., and Mettenleiter, T. C. (2001) Identification and ultrastructural characterization of a novel virus from fish. Journal of General Virology, 82: 2849-2859
Birghan, C., Mundt, E., and Gorbalenya, A. (2000). A non-canonical Lon proteinase deficient of the ATPase domain employs the Ser-Lys catalytic dyad to impose broad control over the life cycle of a double-stranded RNA virus. The EMBO Journal 19, 114-123.
Leong, J. C., Brown, D., Dobos, P., Kibenge, F. S. B., Ludert, J. E., Müller, H., Mundt, E., and Nicholson, B. (2000). Family Birnaviridae. In Virus Taxonomy. Seventh Report of the International Committee on the Taxonomy of Viruses, pp. 481-490. Edited by M. H. V. van Regenmortel, C. M. Fauquet, D. H. L. Bishop, E. B. Carstens, M. K. Estes, S. M. Lemon, J. Maniloff, M. A. Mayo, D. J. McGeoch, C. R. Pringle, and R. B. Wickner, San Diego, San Franscisco, New York, Boston, London, Sydney, and Tokyo: Academic Press
Schröder, A., van Loon, A. A. W. M., Goovaerts, D., and Mundt, E. (2000). Chimeras in noncoding regions between serotypes I and II of segment A of infectious bursal disease virus are viable and show pathogenic phenotype in chickens. Journal of General Virology, 81: 533-540.
Schütze, H., Mundt, E., and Mettenleiter, T.C. (1999). Complete genomic sequence of viral hemorrhagic septicemia virus, a fish rhabdovirus. Virus Genes 19, 59-65.
Mundt, E. (1999). Tissue culture infectivity of different strains of infectious bursal disease virus is determined by distinct amino acids in VP2. Journal of General Virology 80, 2067-2076.
Granzow, H., Weiland, F., Mundt, E., Köllner, B., and Werner, O. (1999). Intranuclear inclusions in cells infected with Newcastle disease virus. Journal of Veterinary Medicine B 46, 411-421.
Römer-Oberdörfer, A., Mundt, E., Mebatsion, T., Buchholz, U. J., and Mettenleiter, T. C. (1999). Generation of recombinant lentogenic Newcastle disease virus from cDNA. Journal of General Virology 80, 2987-2995.
Köllner, B., Mundt, E., and Fischer, U. (1998). A monoclonal antibody recognicing a complex tubular structure in rainbrow trout pillar cells. Journal of Fish Biology 53, 853 – 865.
Granzow, H., Birghan, Ch., Mettenleiter, Th. C., Beyer, J., Köllner, B., and Mundt, E. (1997). A second form of infectious bursal disease virus associated tubules contains VP4. Journal of Virology 71, 8879 – 8885
Mundt, E., Köllner, B., and Kretzschmar, D. (1997). VP5 of infectious bursal disease virus (IBDV) is not essential for viral replication in cell culture. Journal of Virology 71, 5647- 5651.
Schütze, H., Enzmann, P.-J., Mundt, E., and T.C. Mettenleiter (1996). Identification of the non-virion (NV) protein of fish rhabdoviruses viral haemorrhagic septicaemia virus and infectious haematopoietic necrosis virus. Journal of General Virology 77: 1259-1263.
Mundt., E. and Vakharia, V.N. (1996). Synthetic transcripts of double-stranded
birnavirus genome are infectious. Proc. Natl. Acad. Sci. USA 93: 11131-11136.
Mundt, E., Beyer, J., and Müller, H. (1995). Identification of a
novel viral protein in infectious bursal disease virus infected cells.
Journal of General Virology 76: 437-443.
Mundt, E. and Müller, H. (1995). Complete nucleotide sequences of 5`- and 3`- noncoding regions of both genome segments of different strains of infectious bursal disease virus. Virology 209: 209-218.
Schütze, H., Enzmann, P.-J., Kuchling, R., Mundt, E., Niemann, H.,
and T.C. Mettenleiter (1995).
Complete genomic sequence of the fish rhabdovirus infectious haematopoietic
necrosis virus. Journal of General Virology 76: 2519-2527.
Mundt, E., Oberdörfer, A. and Reimann, I. (1994). Reverse transcriptation and polymerase chain reaction - application to diagnosis of viral disease in poultry. Experientia 50: 795.
Book chapter
1. Gorbalenya A.E. und Mundt, E. (2004). Birnavirus VP4 processing endopeptidases.
In Handbook of proteolytical enzymes. 2nd Edition, pp. 1995-1998 Edited
by A. J. Barrett, N. D. Rawlings, J. F. Woessner, Academic Press
2. Modrow, S., Falke, D., and Truyen, U. (2003). Chapter: Birnaviren.
In text book: Molekulare Virologie (in german), pp. 383-388.
3.Mundt, E. (2009). Influenza. In: Lang, F. (Ed). Encyclopedia of Molecular
Mechanisms of Disease. Springer, Berlin Heidelberg New York, pp. 1054-1056.
This page last updated December 2009
