Poultry Diagnostic and Research Center
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50-year Anniversary Celebration
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• Masters of Avian Medicine
• PhD Program in Avian Infectious Diseases
• MS Veterinary & Biomedical Sciences
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Faculty
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College of Veterinary Medicine
|
Associate Professor, Poultry Diagnostic Research Center |
Education
1989 DVM at Humboldt-University in Berlin
1995 Graduation as ‘Dr. med. vet.’
at the University Giessen, (PhD)
2000 Veterinary Specialist for Virology
2002 Graduation (Habilitation) as Dr. rer. med.
habil. for Virology at the University of Greifswald
Professional Experience
1989 – 1991 Employed as scientist at
the Friedrich-Loeffler-Institutes, Insel Riems, Germany. Research
on avian herpesvirus
1991 Research at Institute of Virology, Justus
-Liebig- University Giessen, Germany (Head Prof. Rott)
Aug – Nov. 1995 Visiting scientist at University
of Maryland, Virginia-Maryland Regional College of Veterinary
Medicine, USA
1992-2006 Employed as scientist and group leader
at Federal Research Institute for Animal Health, Insel Riems,
Germany,
Research interests and duties: Research on IBDV, IPNV, Influenza
virus, Newcastle disease virus, fish rabhdoviruses, porcine circovirus
I and II, Trichinella spiralis
Since Aug 1st PDRC, University of Georgia
Membership in scientific boards
Since 1996 Member of the Birnaviridae study
group for international taxonomy of viruses (ICTV)
1998-2004 Member of the management committee
of a COST action of the European union (EU-COST 839 “Immunosuppressive
viral diseases in poultry”,
homepage: http://home.pages.at/cost839/)
1998-2001 Vice-coordinator of the work group
„Vaccination“ of the COST action 839
2001-2004 Coordinator of the work group „Vaccination“
of the COST action 839
since 1999 External referee of the university grants committee
of the University of Hong Kong, China
2005 External referee for PhD thesis University
of Faisalabad, Pakistan
2006 External referee for the Deutsche Forschungsgemeinschaft
(DFG)
Awards
1997 Karl-Fritzsche-Stiftungspreis (Award of
the Karl-Fritzsche-Foundation) awarded from the German Veterinary
Medical Society
2003 Förderpreis 2002 (Award of the German
Academy for Animal Health)
Membership in scientific organizations
German Veterinary Medical Society
American Society for Virology
German Society for Virology
Publications
1. Mundt, E., Oberdörfer, A. and Reimann, I. (1994). Reverse transcriptation
and polymerase chain reaction - application to diagnosis of viral disease
in poultry. Experientia 50: 795.
2. Mundt, E., Beyer, J., and Müller, H. (1995). Identification of
a novel viral protein in infectious bursal disease virus infected cells.
Journal of General Virology 76: 437-443.
3. Mundt, E. and Müller, H. (1995). Complete nucleotide sequences
of 5`- and 3`- noncoding regions of both genome segments of different
strains of infectious bursal disease virus. Virology 209: 209-218.
4. Schütze, H., Enzmann, P.-J., Kuchling, R., Mundt, E., Niemann,
H., and T.C. Mettenleiter (1995). Complete genomic sequence of the fish
rhabdovirus infectious haematopoietic necrosis virus. Journal of General
Virology 76: 2519-2527.
5. Schütze, H., Enzmann, P.-J., Mundt, E., and T.C. Mettenleiter
(1996). Identification of the non-virion (NV) protein of fish rhabdoviruses
viral haemorrhagic septicaemia virus and infectious haematopoietic necrosis
virus. Journal of General Virology 77: 1259-1263.
6. Mundt., E. and Vakharia, V.N. (1996). Synthetic transcripts of double-stranded
birnavirus genome are infectious. Proc. Natl. Acad. Sci. USA 93: 11131-11136.
7. Granzow, H., Birghan, Ch., Mettenleiter, Th. C., Beyer, J., Köllner,
B., and Mundt, E. (1997). A second form of infectious bursal disease virus
associated tubules contains VP4. Journal of Virology 71, 8879 - 8885
8. Mundt, E., Köllner, B., and Kretzschmar, D. (1997). VP5 of infectious
bursal disease virus (IBDV) is not essential for viral replication in
cell culture. Journal of Virology 71, 5647- 5651.
9. Köllner, B., Mundt, E., and Fischer, U. (1998). A monoclonal antibody
recognicing a complex tubular structure in rainbrow trout pillar cells.
Journal of Fish Biology 53, 853 – 865.
10. Schütze, H., Mundt, E., and Mettenleiter, T.C. (1999). Complete
genomic sequence of viral hemorrhagic septicemia virus, a fish rhabdovirus.
Virus Genes 19, 59-65.
11. Mundt, E. (1999). Tissue culture infectivity of different strains
of infectious bursal disease virus is determined by distinct amino acids
in VP2. Journal of General Virology 80, 2067-2076.
12. Granzow, H., Weiland, F., Mundt, E., Köllner, B., and Werner,
O. (1999). Intranuclear inclusions in cells infected with Newcastle disease
virus. Journal of Veterinary Medicine B 46, 411-421.
13. Römer-Oberdörfer, A., Mundt, E., Mebatsion, T., Buchholz,
U. J., and Mettenleiter, T. C. (1999). Generation of recombinant lentogenic
Newcastle disease virus from cDNA. Journal of General Virology 80, 2987-2995.
14. Birghan, C., Mundt, E., and Gorbalenya, A. (2000). A non-canonical
Lon proteinase deficient of the ATPase domain employs the Ser-Lys catalytic
dyad to impose broad control over the life cycle of a double-stranded
RNA virus. The EMBO Journal 19, 114-123.
15. Leong, J. C., Brown, D., Dobos, P., Kibenge, F. S. B., Ludert, J.
E., Müller, H., Mundt, E., and Nicholson, B. (2000). Family Birnaviridae.
In Virus Taxonomy. Seventh Report of the International Committee on the
Taxonomy of Viruses, pp. 481-490. Edited by M. H. V. van Regenmortel,
C. M. Fauquet, D. H. L. Bishop, E. B. Carstens, M. K. Estes, S. M. Lemon,
J. Maniloff, M. A. Mayo, D. J. McGeoch, C. R. Pringle, and R. B. Wickner,
San Diego, San Franscisco, New York, Boston, London, Sydney, and Tokyo:
Academic Press
16. Schröder, A., van Loon, A. A. W. M., Goovaerts, D., and Mundt,
E. (2000). Chimeras in noncoding regions between serotypes I and II of
segment A of infectious bursal disease virus are viable and show pathogenic
phenotype in chickens. Journal of General Virology, 81: 533-540.
17. Schröder, A., van Loon, A. A. W. M., Goovaerts, D., Teifke, J.
P., and Mundt, E. (2001). VP5 and the N terminus of VP2 are not responsible
for the different pathotype of serotype I and II infectious bursal disease
virus. Journal of General Virology, 82: 159-169.
18. Weber, S., Fichtner, D., Mettenleiter, T.C., and Mundt, E. (2001).
Expression of VP5 of infectious pancreatic necrosis virus strain VR299
is initiated at the second in frame startcodon. Journal of General Virology
82:805 – 812
19. Klupp, B. G., Granzow, H., Mundt, E., and Mettenleiter, T. C. (2001).
Pseudorabies virus ul37 gene product is involved in secondary envelopment.
Journal of Virology 75:8927-8936
20. Granzow, H., Weiland, F., Fichtner, D., Schütze, H., Karger,
A., Mundt, E., Dresenkamp, B., Martin, P., and Mettenleiter, T. C. (2001)
Identification and ultrastructural characterization of a novel virus from
fish. Journal of General Virology, 82: 2849-2859
21. van Loon, A. A., de Haas, N. , Zeyda, I. , and Mundt, E. (2002). Alteration
of amino acids in VP2 of very virulent infectious bursal disease virus
results in tissue culture adaptation and attenuation in chickens. Journal
of General Virology 83: 121-129.
22. Kopp, M., Granzow, H., Fuchs, W., Klupp, B. G., Mundt, E., Karger,
A., and Mettenleiter, T. C. (2003). The pseudorabies virus UL11 protein
is a virion component involved in secondary envelopment in the cytoplasm.
Journal of Virology 77, 5339-5351.
23. Zorman-Rojs, O., Barlic-Maganja, D., Mitevski, D., Lubke, W., and
Mundt, E. (2003). Very virulent infectious bursal disease virus in southeastern
Europe. Avian Dis. 47: 186-192.
24. Mundt, E., de Haas, N, and van Loon, A. A. W. M. (2003). Development
of a vaccine for immunization against classical as well as variant strains
of infectious bursal disease virus using reverse genetics. Vaccine, in
press
25. Klupp, B.G., Granzow, H., Fuchs, W., Mundt, E., and Mettenleiter,
T. C. (2004). Pseudorabies Virus UL3 Gene Codes for a Nuclear Protein
Which Is Dispensable for Viral Replication. Journal of Virology 78: 464-472.
26. von Einem, U. I., Gorbalenya, A. E., Schirrmeier, H., Behrens, S.
E., Letzel, T. and Mundt, E.. (2004). VP1 of Infectious Bursal Disease
Virus is a RNA-Dependent RNA Polymerase. Journal of General Virology,
85: 2221-2229.
27. Delmas, B., Kibenge, F.S.B., Leong, J.C., Mundt, E., Vakharia, V.N.
and Wu, J.L. (2004). Birnaviridae. In: Virus Taxonomy, VIIIth Report of
the ICTV (C.M. Fauquet, M.A. Mayo, J. Maniloff, U. Desselberger, and L.A.
Ball, eds), 561-569. Elsevier/Academic Press, London.
28. Wolf, P.U., Uhl, W.Gerst, S., Gerst, K., Klopries, M., Teifke, J.
P., Klopffleisch, R., Harder, T., Werner, O., Hoffmann, B., Starick,.E.,
Mundt, E., Beer, M., Mettenleiter, Th. C. (2006). Letal verlaufende Influenza
bei Hauskatzen nach natürlicher Infektion mit H5N1/Asia in Deutschland.
Deutsches Tierärzteblatt 54, 426-431.
29. Klopfleisch, R., Werner, O., Mundt, E., Harder, T., and Teifke, J.
P. (2006). Neurotropism of highly pathogenic avian influenza virus A/chicken/Indonesia/2003
(H5N1) in experimentally infected pigeons (Columbia livia f. domestica).
Veterinary Pathology. 43, 463-470.
30. Veits, J., Wiesner, D., Fuchs, W., Hoffmann, B., Granzow, H., Starick,
E., Mundt, E., Schirrmeier, H., Mebatsion, T., Mettenleiter T. C., and
Romer-Oberdorfer A. (2006) Newcastle disease virus expressing H5 hemagglutinin
gene protects chickens against Newcastle disease and avian influenza.
Proc Natl Acad Sci U S A. 103, 8197-8202.
31. Jung, D., Teifke. J P., Karger, A., Michael, K. ,Venz, S.,Wittmann,
W., Kindermann, K.,Nöckler, K., and Mundt, E. (2006). Evaluation
of baculovirus-derived recombinant 53 kDa protein of /Trichinella spiralis/
for detection of /Trichinella/-specific antibodies in domestic pigs by
ELISA. Parasitology Research., *published
online:* October, 3, 2006.
32. Weber, S., Harder, T., Starick, E., Beer, M., Werner, O., Hoffmann,
B., Mettenleiter, Th. C., and and Mundt, E. (2006). Molecular analysis
of highly pathogenic avian influenza virus of subtype H5N1 isolated from
wild birds and mammals in Northern Germany. Journal of General Virology,
in press.
33. Starick, E., Werner, O., Schirrmeier, H., Köllner, B., Riebe,
R. and **Mundt, E.* *(2006)*. *Establishment of a competitive ELISA (cELISA)
system for the detection of influenza A virus nucleoprotein antibodies
and its application to field sera from different species. Journal Veterinary
Medicine B 53, 370-375
34. Jung, D., Teifke. J P., Karger, A., Michael, K. ,Venz, S.,Wittmann,
W., Kindermann, K.,Nöckler, K., and Mundt, E. (2007). Evaluation
of baculovirus-derived recombinant 53 kDa protein of Trichinella spiralis
for detection of Trichinella-specific antibodies in domestic pigs by ELISA.
Parasitology Research, 100:429-437.
35. Weber, S., Harder, T., Starick, E., Beer, M., Werner, O., Hoffmann,
B., Mettenleiter, Th. C., and and Mundt, E. (2007). Molecular analysis
of highly pathogenic avian influenza virus of subtype H5N1 isolated from
wild birds and mammals in Northern Germany. Journal of General Virology
88: 554-558.
36. Mundt, E. (2007). Human MxA Protein Confers Resistance to double-stranded
RNA viruses of two virus families. Journal of General Virology, in press
Book Chapter
1. Gorbalenya A.E. und Mundt, E. (2004). Birnavirus VP4 processing endopeptidases.
In Handbook of proteolytical enzymes. 2nd Edition, pp. 1995-1998 Edited
by A. J. Barrett, N. D. Rawlings, J. F. Woessner, Academic Press.
2. Modrow, S., Falke, D., and Truyen, U. (2003). Chapter: Birnaviren.
In text book: Molekulare Virologie (in german), pp. 383-388.
This page last updated March 7, 2007.
